Nobody will want to miss Leighton Meester’s onscreen reunion with husband Adam Brody.

The Gossip Girl alum is set to appear in the upcoming second season of Netflix’s Nobody Wants This as the middle school nemesis of Adam’s onscreen love interest Kristen Bell, the streaming service announced in a post on X (formerly Twitter) Feb. 20.

The casting marks the latest professional collaboration between Leighton, 38, and Adam, 45, who married in 2014 and share two children. The couple previously appeared together in projects like The Oranges, Single Parents and River Wild, and the O.C. actor told E! News in January that he and his wife “always like to work together when it comes up.”

It’s also not the first time Leighton and Kristen have worked together. After the “Somebody to Love” singer appeared on Veronica Mars in a guest role in 2005, Kristen served as the narrator on Gossip Girl throughout its five-season run.